Senior Bioinformatician

Job Description: Senior Bioinformatician
Are you a data-obsessed, full-stack bioinformatician who wants to uncover the key, data-driven insights that will ultimately lead to life-saving medicines? At Aria Pharmaceuticals, we use artificial intelligence to discover lifesaving drug treatments at blazing speed. We are seeking a data scientist to serve as the lead bioinformatician working on the continual development of our world-class drug discovery AI. The ideal candidate is an experienced bioinformatician with broad knowledge of biology, statistics, and programming who is interested in harnessing that knowledge towards discovering novel treatments for a wide diversity of diseases.**

About us:
Aria Pharmaceuticals (formerly twoXAR Pharmaceuticals) is a preclinical-stage pharmaceutical company discovering and developing novel small molecule therapies for complex and hard-to-treat diseases. Too many patients today are in need of breakthrough treatments across many complicated diseases – they can’t wait. That’s why at Aria, we have redefined the drug discovery approach, saving years in the process and increasing success rates 30 times higher than traditional methods. At Aria, we’ve shown promise across a diverse range of therapeutic areas with the ability to address over 1,000 diseases.

Responsibilities

• Serve as the lead full-stack data scientist as we build and enhance the world’s premier AI-driven drug discovery platform
• Develop, extend, and apply innovative computational methods to analyze diverse and heterogeneous biomedical data sources, including most omics types (gene expression, miRNA, methylation, etc.), GWAS, EMR data, systems biology data, and more
• Collaborate with software engineers and drug discovery researchers to implement and extend state-of-the-art algorithms and automated pipelines
• Identify and evaluate potential new biomedical data sources and bioinformatic methodologies
• Work cross-functionally with other internal teams to create and perform end-to-end analyses that include design, data gathering, processing, analysis, iteration with stakeholders, and presentation of results
• Distill complex and heterogeneous data into actionable and interpretable insights

Requirements/Qualifications

• Minimum of M.S. degree in bioinformatics, computational biology, human genetics or a related field, and a sound understanding of both biology and statistics with 5 years independent bioinformatic research experience (PhD fulfills research experience and is a significant plus)
• Experience with statistics, omics, large-scale data ETL & integration, and machine learning is required
• Preference for hands-on experience with packages like Salmon, Limma, VEP, NumPy, and SciKit-Learn
• Proficiency in Python, R, and a Linux environment are required
• Demonstrated problem solving and attention to detail are musts to be successful in this role
• Demonstrated familiarity with best software engineering practices (testing, version control, etc.) is preferred
• Prior experience in an industry R&D environment is a plus
• Demonstrated ability to rapidly learn new concepts
• Startup minded: high energy, low maintenance, self-starter that is comfortable in a fast-paced environment
• Cultural fit: genuine, collaborative, innovative, data-driven, and goal-oriented

Aria Pharmaceuticals is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.