Booking.com plans to lay off up to 25% of workforce

Booking Holdings Inc. said it plans to cut up to a quarter of Booking.com's global workforce, or roughly more than 4,000 people, and restructure the company as the Covid-19 pandemic continues to batter travel demand.

Has the Summit Supercomputer cracked COVID's code?

A supercomputer-powered genetic study of COVID-19 patients has spawned a possible breakthrough into how the novel coronavirus causes disease—and points toward new potential therapies to treat its worst symptoms.

The genetic data mining research uncovered a common pattern of gene activity in the lungs of symptomatic COVID-19 patients, which when compared to gene activity in healthy control populations revealed a mechanism that appears to be a key weapon in the coronavirus’s arsenal.

The good news is there are already drugs—a few of which are already FDA-approved—aimed at some of these very same pathologies.

James Lin

I'm not a bio expert, but this mechanism looks reasonable and fits the evidence. If verified, it could be a game changer.

M. Brook

This would explain why people were worried about the use of popular antihypertensive drugs called ACEI (Angiotensin-Converting Enzyme Inhibitors) – drugs ending with -pril. Bradykinin is broken down by ACE, so inhibiting… Show more

Tuesday

We need to talk about ventilation

How is it that six months into a respiratory pandemic, we are still doing so little to mitigate airborne transmission?

Norman Highnam

Ozone is a good start......