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Grail’s mission is to detect cancer early, when it can be cured

Senior Automation Engineer (Integration & Scale)

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GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is headquartered in Menlo Park, CA with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com.

The Senior/Staff Automation Engineer - Integration and Scale will join a cross-functional development team that includes automation, process, and software engineering, along with R&D scientists, and clinical operations personnel. This team is responsible for transitioning manual and semi-automated workflows to a new fully-automated robotics platform. This position will play a key role in tying together automated laboratory liquid handling systems, robotic workcell automation and robust industrial automation systems into a new NGS-based clinical diagnostic system capable of running millions of patient samples per year. The ideal candidate will be experienced in the integration of components and devices from a wide variety of vendors with custom-built software solutions.

What you'll do:

  • Develop, configure, program, and troubleshoot large scale automated solutions for novel NGS-based clinical diagnostic testing in a regulated environment.
  • Analyze current workflows and develop scalable procedures while identifying new sets of automated equipment to deploy.
  • Be a key contributor to internal cross-functional project teams to develop technical product and automated system requirements.
  • Provide expertise as a conduit to external contractors, suppliers, and integrated system providers in the design of large scale automated solutions.
  • Develop and document work under design control and quality management systems, policies and procedures.
  • Perform research, development, verification and validation testing per project needs.
  • Author, execute and document test plans and Standard Operating Procedures (SOPs) for automated workflows.
  • Support and grow the automation needs of GRAIL Research as needed.
  • Monitor and evaluate new and emerging technologies in laboratory automation systems

About you:

  • B.S. or M.S. in Engineering with preference for Mechanical, Electrical, Chemical, Controls, or Process Engineering or a related Science field with appropriate automation experience.
  • Minimum of 5 years (Senior); 7-10 years (Staff) experience with automation systems and transferring complex workflows into a high-throughput operation. Preference given to experience from the life science industry, but relevant experience from other industries will be considered (e.g. manufacturing in the food & beverage, pharmaceutical, chemical, agricultural, automotive industries)
  • Experience implementing robotic workcells, preferably in a laboratory automation environment.
  • Proven track record leading complex automation projects involving internal and external teams.
  • Demonstrated delivery of automated systems into production environments.
  • Comfortable managing projects and relationships through 3rd party contractors.
  • Analytical, creative thinker, ability to solve problems.
  • Effective organizational and time management skills.
  • Highly energetic and self-motivated. Able to work independently and as part of a team.

Nice to have:

  • Experience writing and optimizing scripts on automated liquid handling platforms (e.g., Hamilton, Tecan, Beckman, etc.)
  • Experience with control systems such as PLCs or other I/O infrastructure (e.g. Allen Bradley, Beckhoff, Siemens, Labview, Arduino, etc.)
  • Experience with the design and prototyping of parts/assemblies using CAD systems (e.g. SolidWorks, Inventor, etc.)
  • Familiarity with manufacturing processes such as 3D printing, machining, injection molding, etc.
  • Experience with NGS or nucleic acid sample preparation methods is desirable.
  • Experience working with a broad set of laboratory instruments and tools.
  • Knowledge of experimental design.
  • Experience working in a regulated environment (CLIA / CAP / FDA / ISO).
  • Experience in reagent manufacturing, ideally in a regulated environment (cGMP).
Menlo Park
Job type
Visa sponsorship
Not Available

Complete health coverage

Take advantage of comprehensive health coverage, with medical, dental and vision, to keep you and your family healthy.

Work-life balance

Make everyday life more manageable with flexible time off – we trust you to do great work and take time for yourself.

On site amenities

Stay healthy, happy and productive with our gym facilities, and daily catered lunches and snacks for all.

Outstanding people

Join a team of passionate and dedicated professionals, committed to collaboration, education, and proactive problem-solving.

Strong compensation

We offer competitive salaries and savings plans to provide peace of mind for long-term financial planning.

GRAIL at a glance

Grail’s mission is to detect cancer early, when it can be cured

GRAIL focuses on Biotechnology, Life Sciences, Healthcare, Diagnostics, and Medical Technologies. Their company has offices in Menlo Park. They have a large team that's between 201-500 employees. To date, GRAIL has raised $3.605B of funding; their latest round was closed on May 2020.

You can view their website at https://grail.com/ or find them on Twitter, Facebook, LinkedIn, and Product Hunt.

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