AngelList

Discover how to get anywhere by searching flights, trains, ferries and driving directions.

Traveling to Sienna in Tuscany? A Google Maps search from San Francisco to Sienna returns no results. Orbitz and Kayak.com won't let you input anything but a large city or airport as your destination. rome2rio displays options of flying to Florence, Bologna or Rome and taking the train to Sienna:
http://www.rome2rio.com?San+Francisco/Sienna

rome2rio can also save you hundreds of dollars. The top Orbitz result for Quebec City to Brussels is often $500 more expensive and 10 hours longer than the top rome2rio result; rome2rio suggests flying direct to Paris and taking a high speed train to Brussels.